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Asymmetric DNA bending in the Cre-loxP site-specific recombination synapse

Cre recombinase catalyzes site-specific recombination between two 34-bp loxP sites in a variety of DNA substrates. At the start of the recombination pathway, the loxP sites are each bound by two recombinase molecules, and synapsis of the sites is mediated by Cre–Cre interactions. We describe the str...

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Detalhes bibliográficos
Main Authors: Guo, Feng, Gopaul, Deshmukh N., Van Duyne, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22031/
https://ncbi.nlm.nih.gov/pubmed/10377382
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