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Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles

RNA molecules have emerged as promising therapeutics. Like all other drugs, the safety profile and immune response are important criteria for drug evaluation. However, the literature on RNA immunogenicity has been controversial. Here, we used the approach of RNA nanotechnology to demonstrate that th...

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Dades bibliogràfiques
Publicat a:Mol Ther Nucleic Acids
Autors principals: Guo, Sijin, Li, Hui, Ma, Mengshi, Fu, Jian, Dong, Yizhou, Guo, Peixuan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701797/
https://ncbi.nlm.nih.gov/pubmed/29246318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.10.010
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