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Oxytocin modulates nociception as an agonist of pain-sensing TRPV1

Oxytocin is a hormone with various actions. Oxytocin-containing parvocellular neurons project to the brainstem and spinal cord. Oxytocin release from these neurons suppresses nociception of inflammatory pain, the molecular mechanism of which remains unclear. Here, we report that the noxious stimulus...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Nersesyan, Yelena, Demirkhanyan, Lusine, Cabezas-Bratesco, Deny, Oakes, Victoria, Kusuda, Ricardo, Dawson, Tyler, Sun, Xiaohui, Cao, Chike, Cohen, Alejandro, Chelluboina, Bharath, Veeravalli, Krishna Kumar, Zimmermann, Katharina, Domene, Carmen, Brauchi, Sebastian, Zakharian, Eleonora
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701661/
https://ncbi.nlm.nih.gov/pubmed/29117570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.063
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