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Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid

TRPV1 channels support the detection of noxious and nociceptive input. Currently available functional and structural data suggest that TRPV1 channels have two gates within their permeation pathway: one formed by a ′bundle-crossing′ at the intracellular entrance and a second constriction at the selec...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Steinberg, Ximena, Kasimova, Marina A, Cabezas-Bratesco, Deny, Galpin, Jason D, Ladron-de-Guevara, Ernesto, Villa, Federica, Carnevale, Vincenzo, Islas, Leon, Ahern, Christopher A, Brauchi, Sebastian E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716661/
https://ncbi.nlm.nih.gov/pubmed/29206105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28626
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