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Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid

TRPV1 channels support the detection of noxious and nociceptive input. Currently available functional and structural data suggest that TRPV1 channels have two gates within their permeation pathway: one formed by a ′bundle-crossing′ at the intracellular entrance and a second constriction at the selec...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Steinberg, Ximena, Kasimova, Marina A, Cabezas-Bratesco, Deny, Galpin, Jason D, Ladron-de-Guevara, Ernesto, Villa, Federica, Carnevale, Vincenzo, Islas, Leon, Ahern, Christopher A, Brauchi, Sebastian E
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716661/
https://ncbi.nlm.nih.gov/pubmed/29206105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28626
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