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Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5)P(2)

Transient receptor potential vanilloid 6 (TRPV6) channels play an important role in Ca(2+) absorption in the intestines. Both phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] and cytoplasmic ATP have been proposed to be important for maintaining TRPV6 activity. To evaluate whether PtdIns(4,5)...

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Detalhes bibliográficos
Main Authors: Zakharian, Eleonora, Cao, Chike, Rohacs, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205842/
https://ncbi.nlm.nih.gov/pubmed/21810903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-184630
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