Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates

BACKGROUND: Siglecs-11 and -16 are members of the sialic acid recognizing Ig-like lectin family, and expressed in same cells. Siglec-11 functions as an inhibitory receptor, whereas Siglec-16 exhibits activating properties. In humans, SIGLEC11 and SIGLEC16 gene sequences are extremely similar in the...

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Vydáno v:BMC Evol Biol
Hlavní autoři: Hayakawa, Toshiyuki, Khedri, Zahra, Schwarz, Flavio, Landig, Corinna, Liang, Suh-Yuen, Yu, Hai, Chen, Xi, Fujito, Naoko T., Satta, Yoko, Varki, Ajit, Angata, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701461/
https://ncbi.nlm.nih.gov/pubmed/29169316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-017-1075-z
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