Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

Background: Pseudomonas species are adapted to evade innate immune responses and can persist at sites of relative tissue hypoxia, including the mucus-plugged airways of patients with cystic fibrosis and bronchiectasis.  The ability of these bacteria to directly sense and respond to changes in local...

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Udgivet i:Wellcome Open Res
Main Authors: Dickinson, Rebecca S., Murphy, Fiona, Doherty, Catherine, Williams, Sam, Mirchandani, Ananda, Willson, Joseph, Scotti, John S., Preston, Gail, Schofield, Christopher J., Whyte, Moira K.B., Walmsley, Sarah R.
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701443/
https://ncbi.nlm.nih.gov/pubmed/29387803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.12871.1
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