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Atypical Creutzfeldt-Jakob disease with PrP-amyloid plaques in white matter: molecular characterization and transmission to bank voles show the M1 strain signature

Amyloid plaques formed by abnormal prion protein (PrP(Sc)) aggregates occur with low frequency in Creutzfeldt-Jakob disease, but represent a pathological hallmark of three relatively rare disease histotypes, namely variant CJD, sporadic CJDMV2K (methionine/valine at PRNP codon 129, PrP(Sc) type 2 an...

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書目詳細資料
發表在:Acta Neuropathol Commun
Main Authors: Rossi, Marcello, Saverioni, Daniela, Di Bari, Michele, Baiardi, Simone, Lemstra, Afina Willemina, Pirisinu, Laura, Capellari, Sabina, Rozemuller, Annemieke, Nonno, Romolo, Parchi, Piero
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701371/
https://ncbi.nlm.nih.gov/pubmed/29169405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0496-7
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