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Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagy
Endoplasmic reticulum (ER) and lysosomes coordinate a network of key cellular processes including unfolded protein response (UPR) and autophagy in response to stress. How ER stress is signaled to lysosomes remains elusive. Here we find that ER disturbance activates chaperone-mediated autophagy (CMA)...
Tallennettuna:
| Julkaisussa: | Nat Commun |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701254/ https://ncbi.nlm.nih.gov/pubmed/29176575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01609-x |
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