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Stress Induces p38 MAPK-mediated Phosphorylation and Inhibition of Drosha-dependent Cell Survival

MicroRNAs (miRNAs) regulate the translational potential of their mRNA targets and control many cellular processes. The key step in canonical miRNA biogenesis is the cleavage of the primary transcripts by the nuclear RNase III enzyme Drosha. Emerging evidence suggests that the miRNA biogenic cascade...

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Dades bibliogràfiques
Publicat a:Mol Cell
Autors principals: Yang, Qian, Li, Wenming, She, Hua, Dou, Juan, Duong, Duc M, Du, Yuhong, Yang, Shao-Hua, Seyfried, Nicholas T., Fu, Haian, Gao, Guodong, Mao, Zixu
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502444/
https://ncbi.nlm.nih.gov/pubmed/25699712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.004
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