Stress Induces p38 MAPK-mediated Phosphorylation and Inhibition of Drosha-dependent Cell Survival

MicroRNAs (miRNAs) regulate the translational potential of their mRNA targets and control many cellular processes. The key step in canonical miRNA biogenesis is the cleavage of the primary transcripts by the nuclear RNase III enzyme Drosha. Emerging evidence suggests that the miRNA biogenic cascade...

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Pubblicato in:Mol Cell
Autori principali: Yang, Qian, Li, Wenming, She, Hua, Dou, Juan, Duong, Duc M, Du, Yuhong, Yang, Shao-Hua, Seyfried, Nicholas T., Fu, Haian, Gao, Guodong, Mao, Zixu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502444/
https://ncbi.nlm.nih.gov/pubmed/25699712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.004
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