Prokaryotic soluble expression and purification of bioactive human fibroblast growth factor 21 using maltose-binding protein

Human fibroblast growth factor 21 (hFGF21) has been characterized as an important regulator of glucose and lipid metabolism homeostasis. Here, to produce hFGF21 efficiently in Escherichia coli, the expression and solubility of hFGF21 were tested and optimised by fusing the protein with one of eight...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Nguyen, Anh Ngoc, Song, Jung-A, Nguyen, Minh Tan, Do, Bich Hang, Kwon, Grace G., Park, Sang Su, Yoo, Jiwon, Jang, Jaepyeong, Jin, Jonghwa, Osborn, Mark J., Jang, Yeon Jin, Thi Vu, Thu Trang, Oh, Heung-Bum, Choe, Han
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700921/
https://ncbi.nlm.nih.gov/pubmed/29170489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16167-x
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