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Aptamers as targeted therapeutics: current potential and challenges

Nucleic acid aptamers, often termed “chemical antibodies”, are functionally comparable to traditional antibodies, but offer several advantages including their relatively small physical size, flexible structure, quick chemical production, versatile chemical modification, high stability, and lack of i...

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Bibliografiske detaljer
Udgivet i:Nat Rev Drug Discov
Main Authors: Zhou, Jiehua, Rossi, John
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700751/
https://ncbi.nlm.nih.gov/pubmed/27807347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.199
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