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Aptamers as targeted therapeutics: current potential and challenges

Nucleic acid aptamers, often termed “chemical antibodies”, are functionally comparable to traditional antibodies, but offer several advantages including their relatively small physical size, flexible structure, quick chemical production, versatile chemical modification, high stability, and lack of i...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Zhou, Jiehua, Rossi, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700751/
https://ncbi.nlm.nih.gov/pubmed/27807347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.199
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