Current progress of RNA aptamer-based therapeutics

Aptamers are single-stranded nucleic acids that specifically recognize and bind tightly to their cognate targets due to their stable three-dimensional structure. Nucleic acid aptamers have been developed for various applications, including diagnostics, molecular imaging, biomarker discovery, target...

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Bibliografiske detaljer
Main Authors: Jiehua eZhou, Maggie eBobbin, John C. Burnett, John Joseph Rossi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2012-11-01
Serier:Frontiers in Genetics
Fag:
RNAi
siRNA
SELEX
RNA aptamers
targeted delivery
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00234/full
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