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RNA editing of SLC22A3 mRNAs: causative relevance to familial ESCC?

A new study reveals an involvement of SLC22A3 in the development of familial oesophageal squamous cell carcinoma (ESCC). Reduced expression of SLC22A3 is detected not only in ESCC tumours but also in non-tumour tissues of patients with familial ESCC. Interestingly, adenosine-to-inosine editing of SL...

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Pubblicato in:Nat Rev Gastroenterol Hepatol
Autore principale: Nishikura, Kazuko
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700748/
https://ncbi.nlm.nih.gov/pubmed/28743982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrgastro.2017.102
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