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Functional relevance of serotonin 2C receptor mRNA editing in antidepressant- and anxiety-like behaviors

Serotonin 2C receptors (5-HT(2C)R) have been shown to undergo post-transcriptional RNA editing. This modification affects the affinity, coupling and constitutive activity of the receptor. In vivo, manipulations such as stress or antidepressant administration dramatically modify the pattern of 5-HT(2...

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Detalhes bibliográficos
Main Authors: Mombereau, Cedric, Kawahara, Yukio, Gundersen, Brigitta B., Nishikura, Kazuko, Blendy, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946438/
https://ncbi.nlm.nih.gov/pubmed/20624407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.06.009
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