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Functional relevance of serotonin 2C receptor mRNA editing in antidepressant- and anxiety-like behaviors
Serotonin 2C receptors (5-HT(2C)R) have been shown to undergo post-transcriptional RNA editing. This modification affects the affinity, coupling and constitutive activity of the receptor. In vivo, manipulations such as stress or antidepressant administration dramatically modify the pattern of 5-HT(2...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946438/ https://ncbi.nlm.nih.gov/pubmed/20624407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.06.009 |
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