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RNA editing of SLC22A3 mRNAs: causative relevance to familial ESCC?

A new study reveals an involvement of SLC22A3 in the development of familial oesophageal squamous cell carcinoma (ESCC). Reduced expression of SLC22A3 is detected not only in ESCC tumours but also in non-tumour tissues of patients with familial ESCC. Interestingly, adenosine-to-inosine editing of SL...

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Detalhes bibliográficos
Publicado no:Nat Rev Gastroenterol Hepatol
Autor principal: Nishikura, Kazuko
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700748/
https://ncbi.nlm.nih.gov/pubmed/28743982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrgastro.2017.102
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