Mapping Hydrophobic Tunnels and Cavities in Neuroglobin with Noble Gas under Pressure

Internal cavities are crucial for conformational flexibility of proteins and can be mapped through noble gas diffusion and docking. Here we investigate the hydrophobic cavities and tunnel network in neuroglobin (Ngb), a hexacoordinated heme protein likely to be involved in neuroprotection, using cry...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Colloc’h, Nathalie, Carpentier, Philippe, Montemiglio, Laura C., Vallone, Beatrice, Prangé, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700381/
https://ncbi.nlm.nih.gov/pubmed/29108649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.014
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