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The Structure of Neuroglobin at High Xe and Kr Pressure Reveals Partial Conservation of Globin Internal Cavities

Neuroglobin (Ngb) is a hexacoordinate globin expressed in the brain of vertebrates. Ferrous Ngb binds dioxygen with high affinity and the O(2) adduct is able to scavenge NO. Convincing in vitro and in vivo data indicate that Ngb is involved in neuroprotection during hypoxia and ischemia. The 3D stru...

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Hlavní autoři: Moschetti, Tommaso, Mueller, Uwe, Schulze, Jörg, Brunori, Maurizio, Vallone, Beatrice
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741589/
https://ncbi.nlm.nih.gov/pubmed/19751675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.059
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