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Azide inhibition of urate oxidase

The inhibition of urate oxidase (UOX) by azide was investigated by X-ray diffraction techniques and compared with cyanide inhibition. Two well characterized sites for reagents are present in the enzyme: the dioxygen site and the substrate-binding site. To examine the selectivity of these sites towar...

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Bibliografiske detaljer
Main Authors: Gabison, Laure, Colloc’h, Nathalie, Prangé, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089527/
https://ncbi.nlm.nih.gov/pubmed/25005084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14011753
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