A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum

Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria, particularly in light of developing resistance to partner drugs. Improving our understanding of how artemisinin-based drugs act and how resistance manifests is essential for the optimization o...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Cao, Pengxing, Klonis, Nectarios, Zaloumis, Sophie, Dogovski, Con, Xie, Stanley C., Saralamba, Sompob, White, Lisa J., Fowkes, Freya J. I., Tilley, Leann, Simpson, Julie A., McCaw, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700357/
https://ncbi.nlm.nih.gov/pubmed/28993326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00618-17
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