Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi

Isavuconazole, the active moiety of the water-soluble prodrug isavuconazonium sulfate, is a triazole antifungal agent for the treatment of invasive fungal infections. The purpose of this analysis was to characterize the isavuconazole exposure-response relationship for measures of efficacy and safety...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Desai, Amit V., Kovanda, Laura L., Hope, William W., Andes, David, Mouton, Johan W., Kowalski, Donna L., Townsend, Robert W., Mujais, Salim, Bonate, Peter L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700339/
https://ncbi.nlm.nih.gov/pubmed/28923872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01034-17
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