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Temporal changes in glutathione biosynthesis during the lipopolysaccharide-induced inflammatory response of THP-1 macrophages

How macrophages maintain redox homeostasis in the inflammatory process, in which a large amount of oxidants are produced, remains elusive. In this study, we investigated the temporal changes in the intracellular glutathione (GSH), the master antioxidant, and the expression of glutamate cysteine liga...

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Bibliografske podrobnosti
izdano v:Free Radic Biol Med
Main Authors: Zhang, Hongqiao, Liu, Honglei, Zhou, Lulu, Yuen, Jenay, Forman, Henry Jay
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699958/
https://ncbi.nlm.nih.gov/pubmed/28993271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.10.010
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