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Down regulation of glutathione and glutamate cysteine ligase in the inflammatory response of macrophages

Glutathione (GSH) plays critical roles in the inflammatory response by acting as the master substrate for antioxidant enzymes and an important anti-inflammatory agent. In the early phase of the inflammatory response of macrophages, GSH content is decreased due to the down regulation of the catalytic...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Zhang, Hongqiao, Zhang, Sarah (Jiuqi), Lyn, Natalie, Florentino, Abigail, Li, Andrew, Davies, Kelvin, J.A., Forman, Henry Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484362/
https://ncbi.nlm.nih.gov/pubmed/32682927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.06.017
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