Llwytho...
Sampling and energy evaluation challenges in ligand binding protein design
The steroid hormone 17α‐hydroxylprogesterone (17‐OHP) is a biomarker for congenital adrenal hyperplasia and hence there is considerable interest in development of sensors for this compound. We used computational protein design to generate protein models with binding sites for 17‐OHP containing an ex...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Protein Sci |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
John Wiley and Sons Inc.
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699494/ https://ncbi.nlm.nih.gov/pubmed/28980354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3317 |
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