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Modulating protein activity using tethered ligands with mutually exclusive binding sites
The possibility to design proteins whose activities can be switched on and off by unrelated effector molecules would enable applications in various research areas, ranging from biosensing to synthetic biology. We describe here a general method to modulate the activity of a protein in response to the...
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Publicado no: | Nat Commun |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Pub. Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525150/ https://ncbi.nlm.nih.gov/pubmed/26198003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8830 |
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