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Large cosolutes, small cosolutes, and dihydrofolate reductase activity

Protein enzymes are the main catalysts in the crowded and complex cellular interior, but their activity is almost always studied in dilute buffered solutions. Studies that attempt to recreate the cellular interior in vitro often utilize synthetic polymers as crowding agents. Here, we report the effe...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Acosta, Luis C., Perez Goncalves, Gerardo M., Pielak, Gary J., Gorensek‐Benitez, Annelise H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699487/
https://ncbi.nlm.nih.gov/pubmed/28971539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3316
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