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Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin

During biofilm formation, Escherichia coli and other Enterobacteriaceae produce an extracellular matrix consisting of curli amyloid fibers and cellulose. The precursor of curli fibers is the amyloidogenic protein CsgA. The human systemic amyloid precursor protein transthyretin (TTR) is known to inhi...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Jain, Neha, Ådén, Jörgen, Nagamatsu, Kanna, Evans, Margery L., Li, Xinyi, McMichael, Brennan, Ivanova, Magdalena I., Almqvist, Fredrik, Buxbaum, Joel N., Chapman, Matthew R.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699053/
https://ncbi.nlm.nih.gov/pubmed/29087319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708805114
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