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Parsing the roles of neck-linker docking and tethered head diffusion in the stepping dynamics of kinesin
Kinesin walks processively on microtubules (MTs) in an asymmetric hand-over-hand manner consuming one ATP molecule per 16-nm step. The individual contributions due to docking of the approximately 13-residue neck linker to the leading head (deemed to be the power stroke) and diffusion of the trailing...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699036/ https://ncbi.nlm.nih.gov/pubmed/29087307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706014114 |
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