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Population pharmacokinetic meta‐analysis of ramucirumab in cancer patients

AIMS: Ramucirumab is a human IgG1 monoclonal antibody that specifically binds vascular endothelial growth factor receptor‐2 (VEGFR‐2) and blocks binding of VEGF‐A, VEGF‐C and VEGF‐D. The objective of the analysis was to characterize the clinical pharmacology profile of ramucirumab using a population...

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Pubblicato in:Br J Clin Pharmacol
Autori principali: O'Brien, Lisa, Westwood, Paul, Gao, Ling, Heathman, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698573/
https://ncbi.nlm.nih.gov/pubmed/28833321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13403
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