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Population pharmacokinetic meta‐analysis of ramucirumab in cancer patients

AIMS: Ramucirumab is a human IgG1 monoclonal antibody that specifically binds vascular endothelial growth factor receptor‐2 (VEGFR‐2) and blocks binding of VEGF‐A, VEGF‐C and VEGF‐D. The objective of the analysis was to characterize the clinical pharmacology profile of ramucirumab using a population...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: O'Brien, Lisa, Westwood, Paul, Gao, Ling, Heathman, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698573/
https://ncbi.nlm.nih.gov/pubmed/28833321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13403
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