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Population pharmacokinetics of APOMINE™: A meta-analysis in cancer patients and healthy males

AIMS: 1) To characterize the population pharmacokinetics of apomine in healthy males and in male and female patients with solid tumours and 2) to understand more fully the influence of induction and between- and within-subject variability on exposure to drug using Monte Carlo simulation. METHODS: Ap...

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Autori principali: Bonate, Peter L, Floret, Simon, Bentzen, Craig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884594/
https://ncbi.nlm.nih.gov/pubmed/15255796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2004.02111.x
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