Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling

Nitroxyl anion (NO(−)) is the one-electron reduction product of nitric oxide (NO(⋅)) and is enzymatically generated by NO synthase in vitro. The physiologic activity and mechanism of action of NO(−) in vivo remains unknown. The NO(−) generator Angeli's salt (AS, Na(2)N(2)O(3)) was administered to co...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Paolocci, Nazareno, Saavedra, Walter F., Miranda, Katrina M., Martignani, Cristian, Isoda, Takayoshi, Hare, Joshua M., Espey, Michael G., Fukuto, Jon M., Feelisch, Martin, Wink, David A., Kass, David A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11517312/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.181191198
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