Positive inotropic and lusitropic effects of HNO/NO(−) in failing hearts: Independence from β-adrenergic signaling

Nitroxyl anion (HNO/NO(−)), the one-electron reduced form of nitric oxide (NO), induces positive cardiac inotropy and selective venodilation in the normal in vivo circulation. Here we tested whether HNO/NO(−) augments systolic and diastolic function of failing hearts, and whether contrary to NO/nitr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Paolocci, Nazareno, Katori, Tatsuo, Champion, Hunter C., St. John, Marcus E., Miranda, Katrina M., Fukuto, Jon M., Wink, David A., Kass, David A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0937302100
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