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IFN-λ4 attenuates antiviral responses by enhancing negative regulation of interferon signaling
Type-III interferons (IFNs) are important mediators of antiviral immunity. IFN-λ4 is a unique type-III IFN because it is produced only in individuals who carry a dG allele of a genetic variant rs368234815-dG/TT. Counterintuitively, those individuals who can produce IFN-λ4, an antiviral cytokine, are...
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| 出版年: | J Immunol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698113/ https://ncbi.nlm.nih.gov/pubmed/29070670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700807 |
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