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IFN-λ4: The Paradoxical New Member of the Interferon Lambda Family

Interferons (IFNs) are generally considered antiviral cytokines, yet the newly discovered IFN-λ4 is linked with the failure to clear hepatitis C virus (HCV) infection either spontaneously or in response to treatment. IFN-λ4 can be generated only by individuals who carry the IFNL4-ΔG allele (rs368234...

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Autors principals: O'Brien, Thomas R., Prokunina-Olsson, Ludmila, Donnelly, Raymond P.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217005/
https://ncbi.nlm.nih.gov/pubmed/24786669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2013.0136
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