Genetic NMDA receptor deficiency disrupts acute and chronic effects of cocaine but not amphetamine

NMDA receptor-mediated glutamate transmission is required for several forms of neuronal plasticity. Its role in the neuronal responses to addictive drugs is an ongoing subject of investigation. We report here that the acute locomotor-stimulating effect of cocaine is absent in NMDA-receptor deficient...

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Publicado en:Neuropsychopharmacology
Autores principales: Ramsey, Amy J., Laakso, Aki, Cyr, Michel, Sotnikova, Tatyana D., Salahpour, Ali, Medvedev, Ivan O., Dykstra, Linda A., Gainetdinov, Raul R., Caron, Marc G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698087/
https://ncbi.nlm.nih.gov/pubmed/18185498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301663
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