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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

The t(8;21) is one of the most frequent chromosomal abnormalities associated with acute myeloid leukemia (AML). The translocation, which involves the AML1 gene on chromosome 21 and the ETO gene on chromosome 8, generates an AML1-ETO fusion transcription factor. To examine the effect of the AML1-ETO...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Yuan, Youzhong, Zhou, Liming, Miyamoto, Toshihiro, Iwasaki, Hiromi, Harakawa, Nari, Hetherington, Christopher J., Burel, Sebastien A., Lagasse, Eric, Weissman, Irving L., Akashi, Koichi, Zhang, Dong-Er
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2001
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11526243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.171321298
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