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Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice

Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD). Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production. We investigated the role of GA in the progression of renal injury in DN. Albumin (Alb)/creatinine (crea) levels were significant...

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Bibliografische gegevens
Gepubliceerd in:J Diabetes Res
Hoofdauteurs: Hou, Shaozhang, Zhang, Ting, Li, Yuan, Guo, Fengying, Jin, Xiu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697128/
https://ncbi.nlm.nih.gov/pubmed/29238727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2865912
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