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Calcium binding and voltage gating in Cx46 hemichannels
The opening of connexin (Cx) hemichannels in the membrane is tightly regulated by calcium (Ca(2+)) and membrane voltage. Electrophysiological and atomic force microscopy experiments indicate that Ca(2+) stabilizes the hemichannel closed state. However, structural data show that Ca(2+) binding induce...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696461/ https://ncbi.nlm.nih.gov/pubmed/29158540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15975-5 |
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