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Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ

DNA damage impinges on genetic information flow and has significant implications in human disease and aging. Lucidin-3-O-primeveroside (LuP) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. LuP can be metabolically converted to genotox...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Yockey, Oliver P., Jha, Vikash, Ghodke, Pratibha P., Xu, Tianzuo, Xu, Wenyan, Ling, Hong, Pradeepkumar, P. I., Zhao, Linlin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696069/
https://ncbi.nlm.nih.gov/pubmed/28972744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00227
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