Hypoxia inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development

Hypoxia in the embryo is a frequent cause of intra-uterine growth retardation, low birth weight and multiple organ defects. In the kidney this can lead to low nephron endowment predisposing to chronic kidney disease and arterial hypertension. A key component in cellular adaptation to hypoxia is the...

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Vydáno v:Kidney Int
Hlavní autoři: Kobayashi, Hanako, Liu, Jiao, Urrutia, Andres A., Burmakin, Mikhail, Ishii, Ken, Rajan, Malini, Davidoff, Olena, Saifudeen, Zubaida, Haase, Volker H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696043/
https://ncbi.nlm.nih.gov/pubmed/28847650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.06.015
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