Tubulointerstitial fibrosis can sensitize the kidney to subsequent glomerular injury

Chronic glomerular injury is associated with eventual development of tubulointerstitial fibrosis. Here we aimed to assess whether, and how, mild chronic tubulointerstitial injury affects glomeruli. For this, we generated mice expressing different toxin receptors, one on their proximal tubular epithe...

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Publicado en:Kidney Int
Autores principales: Lim, Beom Jin, Yang, Jae won, Zou, Jun, Zhong, Jianyong, Matsusaka, Taiji, Pastan, Ira, Zhang, Ming-Zhi, Harris, Raymond C., Yang, Hai-Chun, Fogo, Agnes B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696028/
https://ncbi.nlm.nih.gov/pubmed/28709637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.04.010
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