Stabilization of Hypoxia-Inducible Factor Ameliorates Glomerular Injury Sensitization after Tubulointerstitial Injury

Previously, we found that mild tubulointerstitial injury sensitizes glomeruli to subsequent injury. Here, we evaluated whether stabilization of hypoxia-inducible factor-α (HIF-α), a key regulator of tissue response to hypoxia, ameliorates tubulointerstitial injury and impact on subsequent glomerular...

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Vydáno v:Kidney Int
Hlavní autoři: Zou, Jun, Yang, Jaewon, Zhu, Xiaoye, Zhong, Jianyong, Elshaer, Ahmed, Matsusaka, Taiji, Pastan, Ira, Haase, Volker H., Yang, Hai-Chun, Fogo, Agnes B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7914150/
https://ncbi.nlm.nih.gov/pubmed/33137336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2020.09.031
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