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Genome-guided identification of novel head-to-tail cyclized antimicrobial peptides, exemplified by the discovery of pumilarin

The need for novel antibiotics in an era where antimicrobial resistance is on the rise, and the number of new approved antimicrobial drugs reaching the market is declining, is evident. The underused potential of post-translationally modified peptides for clinical use makes this class of peptides int...

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Detalhes bibliográficos
Publicado no:Microb Genom
Main Authors: van Heel, Auke J., Montalban-Lopez, Manuel, Oliveau, Quentin, Kuipers, Oscar P.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695211/
https://ncbi.nlm.nih.gov/pubmed/29177092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mgen.0.000134
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