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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

The d, ash, and ln coat color mutations provide a unique model system for the study of vesicle transport in mammals. All three mutant loci encode genes that are required for the polarized transport of melanosomes, the specialized, pigment-containing organelles of melanocytes, to the neighboring kera...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Matesic, Lydia E., Yip, Richard, Reuss, Andreé E., Swing, Deborah A., O'Sullivan, T. Norene, Fletcher, Colin F., Copeland, Neal G., Jenkins, Nancy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC56945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11504925/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.181336698
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