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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice
The d, ash, and ln coat color mutations provide a unique model system for the study of vesicle transport in mammals. All three mutant loci encode genes that are required for the polarized transport of melanosomes, the specialized, pigment-containing organelles of melanocytes, to the neighboring kera...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56945/ https://ncbi.nlm.nih.gov/pubmed/11504925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181336698 |
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