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Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

The d, ash, and ln coat color mutations provide a unique model system for the study of vesicle transport in mammals. All three mutant loci encode genes that are required for the polarized transport of melanosomes, the specialized, pigment-containing organelles of melanocytes, to the neighboring kera...

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Detalhes bibliográficos
Main Authors: Matesic, Lydia E., Yip, Richard, Reuss, Andreé E., Swing, Deborah A., O'Sullivan, T. Norene, Fletcher, Colin F., Copeland, Neal G., Jenkins, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56945/
https://ncbi.nlm.nih.gov/pubmed/11504925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181336698
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