Necroptosis is associated with Rab27‐independent expulsion of extracellular vesicles containing RIPK3 and MLKL

Abstract Extracellular vesicle (EV) secretion is an important mechanism used by cells to release biomolecules. A common necroptosis effector—mixed lineage kinase domain like (MLKL)—was recently found to participate in the biogenesis of small and large EVs independent of its function in necroptosis....

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Detalhes bibliográficos

Principais autores:	Kartik Gupta, Kyle A. Brown, Marvin L. Hsieh, Brandon M. Hoover, Jianxin Wang, Mitri K. Khoury, Vijaya Satish Sekhar Pilli, Reagan S. H. Beyer, Nihal R. Voruganti, Sahil Chaudhary, David S. Roberts, Regina M. Murphy, Seungpyo Hong, Ying Ge, Bo Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-09-01
coleção:	Journal of Extracellular Vesicles
Assuntos:	lysosomal exocytosis MLKL necroptosis proteomics RIPK3 SEVs
Acesso em linha:	https://doi.org/10.1002/jev2.12261
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